Biology Category
Use chemistry to understand and control biology — small-molecule probes, chemical synthesis of biomolecules, chemical genetics, and drug discovery.
Welcome to the Chemical Biology category of this site. Here you will find clear, detailed articles covering key topics related to Chemical Biology.
A detailed guide to activity based protein profiling. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to antibody-drug conjugates. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to antisense oligonucleotide therapeutics. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to biological activity of metal complexes. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to bioorthogonal chemistry. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to caged compounds and photochemistry. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to cell penetrating peptides. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical chaperones and protein folding. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical genetics and forward screens. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical glycobiology. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical inducers of dimerization. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical synthesis of oligonucleotides. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical synthesis of proteins. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical tools for epigenetics. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical tools for ion channel biology. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemical tools for kinase biology. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemically induced proximity. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to chemogenetics for neuronal control. Covers key mechanisms, biological significance, and clinical relevance.
Learn about chemoproteomics — covering SILAC labeling, TMT quantitation, and the role of chemical proteomics in this fundamental biological process.
A detailed guide to chemotherapy drug mechanisms. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to click chemistry in biology. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to covalent drug discovery. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to designing small molecule probes. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to dna and rna chemical modification. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to fluorescent probes and imaging. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to foundations of chemical biology. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to fragment based drug discovery. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to genetically encoded fluorescent sensors. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to high throughput screening in drug discovery. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to kinase inhibitors as therapeutics. Covers key mechanisms, biological significance, and clinical relevance.
Learn about lipid chemical biology — covering clickable lipid analogs, lipid rafts, and the role of lipid probes in this fundamental biological process.
A detailed guide to macrocyclic drugs and constrained peptides. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to mass spectrometry in chemical biology. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to metabolic labeling with sugar analogs. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to mrna chemical modification and delivery. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to natural products and drug leads. Covers key mechanisms, biological significance, and clinical relevance.
Learn about nucleic acid aptamers — covering RNA folding, aptamer selection rounds, and the role of SELEX in this fundamental biological process.
A detailed guide to peptide stapling chemistry. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to photoaffinity labeling of receptors. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to photocrosslinking probes. Covers key mechanisms, biological significance, and clinical relevance.
Learn about platinum anticancer agents — covering nuclear DNA binding, repair pathways, and the role of cisplatin in this fundamental biological process.
A detailed guide to polyketide biosynthesis. Covers key mechanisms, biological significance, and clinical relevance.
Learn about protacs and targeted protein degradation — covering degron tags, hook effect, and the role of PROTACs in this fundamental biological process.
A detailed guide to ribosome display and molecular evolution. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to small molecule fluorescent labels. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to staudinger ligation and reactions. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to structure based drug design. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to suicide inhibitors and mechanism based inactivation. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to target identification for bioactive compounds. Covers key mechanisms, biological significance, and clinical relevance.
A detailed guide to transition state analog inhibitors. Covers key mechanisms, biological significance, and clinical relevance.
